Biomaterials

Biomaterials for Gene and Cell Therapy

Biomaterials play a pivotal role in advancing gene and cell therapy by providing essential support for the delivery, protection, and function of therapeutic genes and cells. In gene therapy, biomaterials such as nanoparticles, liposomes, and hydrogels are engineered to encapsulate and deliver genetic material (e.g., plasmids or RNA) to target cells efficiently. These materials ensure controlled release and protect the therapeutic genes from degradation, enhancing the efficacy of gene delivery. For cell therapy, biomaterials offer a supportive scaffold for cell growth and differentiation. Scaffolds made from natural or synthetic polymers create an environment that mimics the extracellular matrix, promoting cell attachment and tissue formation. Additionally, biomaterials can be functionalized with bioactive molecules to guide cell behavior and integration. Overall, the integration of biomaterials into gene and cell therapies enhances precision, improves therapeutic outcomes, and advances the development of personalized treatments for a variety of diseases.