Mehmet Bayrak
Ortadogu Private Hospital, Turkey
Title: Permacol â„¢ collagen paste injection in anal fistula treatment: retrospective study with eighteen months follow-up
Biography
Biography: Mehmet Bayrak
Abstract
Introduction: This study aimed to evaluate the applicability, safety, results, and functional performance of Permacol™ collagen paste injection in patients with an anal fistula.
Methods: Thirty-nine patients with anal fistula underwent Permacol™ collagen paste injection between February 2015 and February 2018. The patients were followed up for a total of 18months with intervals of 3, 6, 12 and 18 month recovery conditions monitored. Fifteen patients for a period of 6–8 weeks and two patients for a period of 12 weeks underwent preoperative
insertion of seton.
Results: A transsphincteric anal fistula was present in 20 patients, and an intersphincteric fistula was present in 11 patients. There was a recurrence in 7 patients (17.9%): 1 patient (2.5%) after 1-month follow-up, 3 patients (7.6%) after 3-month follow-up, 2 patients (5.1%) after 6-month follow-up, and 1 patient (2.5%) after 18-month follow-up. A complete recovery was observed in 32(82.0%) patients after a 18-month follow-up. The mean Fecal Incontinence Severity Index (FISI) score was 0.29±0.64 preoperatively and 0.55±1.03 after 12 months.
Conclusion: In this study, we show that Permacol™ is a safe and successful method that does not compromise continence following injection and treatment of patients with an anal fistula.